Dull, dry, lackluster skin with wrinkles becoming more visible every day. No matter how well you take care of yourself — applying creams, skincare products, or taking supplements — your skin may still not respond as expected.
As we age, the body gradually produces less collagen naturally, causing the skin to lose elasticity, firmness, and smoothness. The collagen that once nourished the skin structure decreases naturally, making skin thinner, sagging, and more prone to wrinkles.
At Orianna Clinic, we believe that good skincare doesn't start with just external filling, but should begin with properly restoring the skin structure from within. Today, Orianna Clinic introduces another option for skincare with the CollaJu Program — a Biostimulator program designed to stimulate collagen production in the skin for firmer, smoother, and naturally healthier-looking results.

Program CollaJu Baby Collagen
What is the Collaju Program?
Collaju® is a collagen product for skin rejuvenation (Collagen Rejuvenation) with the main ingredient being Atelocollagen Type-1 at a concentration of 3% — a highly pure collagen that fills gaps in the skin layers caused by age-related collagen loss. With innovation free from allergens and impurities, it can restore skin deep to the cellular level.
Collaju can fill immediately without requiring stimulation from the body and doesn't destroy existing skin tissue. It helps restore deteriorated skin to become strong, firm, and naturally smooth again.
CollaJu is a Biostimulator program designed to stimulate the skin's collagen production from within — not filling, not pulling, but "awakening the skin's natural restoration mechanism."
Is the Collaju Program Safe?
Key components of Collaju® that make it an effective collagen replacement:
1. Raw Materials (High-Quality Ingredients): Uses internationally standardized raw material management systems, certified with CE and ISO13485 medical device standards.
2. Free of Antigenicity and Impurities: Minimizes immune response and inflammation through enzyme treatment and multi-layer safe filtration systems.
3. Excellent Biocompatibility: Uses patented Aseptic Salt Precipitation process (Patent No. 10-1106543). The collagen produced is human-like, non-crosslinked, with consistent diameter and pH maintained in the skin-appropriate range (7.5 - 7.9).

Collaju Raw Materials and Biocompatibility
What is the Structure of the Collaju Program?
Collaju® uses a biological process with Pepsin enzyme to cut the Telopeptide ends while maintaining the main collagen structure as a complete Triple Helix. This results in high-purity Atelocollagen Type I that is free from allergenic parts and highly compatible with human skin tissue.
After injection, CollaJu works at the Dermal – Subdermal Layer with 3 main mechanisms:
1. Stimulates Fibroblast → Collagen-producing cells are activated to resume working
2. Increases ECM (Extracellular Matrix) Structure → Skin becomes firmer, more elastic, and stronger
3. New Collagen is Continuously Produced → Skin looks younger without looking "done"
CollaJu doesn't change your face shape — it makes your skin look better in its own version.
What Are the Key Advantages of Collaju?
1. Stimulates Natural Collagen Production — Atelocollagen Type I not only fills the skin but also stimulates Fibroblast cells to promote collagen production from within.
2. Smooth and Natural Results — Non-crosslinked collagen doesn't clump, providing smooth, non-stiff, natural-looking results.
3. High Safety — Processed through Aseptic Salt Precipitation for high-purity collagen free from immunogenic substances.
4. Longer-Lasting Results — Collaju® not only fills immediately but also stimulates the body to continuously produce collagen.
5. Can Be Used in Multiple Body Areas — Beyond the face, it can be used on the neck, back of hands, or other areas with thin, sagging skin.
6. Promotes Overall Skin Health — Increases moisture, makes skin smoother, brighter, and more elastic, even in areas without deep lines.
What Problems is Collaju Suitable For?

ปัญหาผิวที่แก้ได้ด้วย CollaJu
Collaju® is suitable for:
1. Those with sagging skin — droopy eyelids, sunken cheeks, drooping mouth corners
2. Those with wrinkles and deep lines — crow's feet, cheek grooves, forehead wrinkles
3. Those with thin, sensitive skin
4. Those with dry, rough skin lacking moisture
5. Those with enlarged pores
6. Those with slow-healing wounds or acne scars
7. Those with unclear facial contours
8. Those who want natural skin restoration without changing facial structure
Where Can Collaju Be Injected?
Areas suitable for the CollaJu program:
- Full Face (Full Face Quality)
- Under Eyes (suitable for thin skin)
- Neck and Décolletage
- Back of Hands, forehead grooves
- Areas where skin is thinning, sagging, or losing elasticity
What Are the Injection Methods?

Pure Collagen Filler และ Collagen Skin Boost Up
Collaju can be injected in 2 functions: Pure Collagen Filler and Collagen Skin Boost Up
1. Pure Collagen Filler
Function: Volumizing Rejuvenation — used as a filler to add volume in the skin layers
Under-eye area:
- Injection layer: Subdermal Layer
- Cannula size 25G–27G
- Technique: Fanning (Retrograde injection 0.01–0.03 ml per point)
Deep forehead grooves (horizontal):
- Injection layer: Hypodermal Layer
- Needle size 27G
- Technique: Linear (Retrograde injection 0.01–0.03 ml per point)
2. Collagen Skin Boost Up
Function: Natural Volumizing and Rejuvenation — light skin filling to stimulate moisture and smoothness
- Formula: Collaju® 1 cc + NSS (Normal Saline Solution) 2 cc
- Injection layer: Intradermal Layer
- Needle size: 30G–32G
- Technique: Point by Point Injection
Post-Treatment Care

การดูแลหลังทำโปรแกรม Collaju
Post-treatment care is essential for effective collagen stimulation and proper skin recovery.
First 24 Hours (Initial Recovery)
- Avoid pressing, massaging, or kneading the injection area
- If swelling occurs, cold compress for 10–15 minutes at a time
- Get adequate rest and sleep with a slightly elevated pillow
- Avoid all heat sources such as hot water, sauna, or steam
First 1–2 Days
- Avoid heavy exercise or activities causing excessive sweating
- Avoid alcohol and smoking
- Use gentle skincare products
1–2 Weeks After Treatment
- Avoid heat-based procedures such as laser, RF, HIFU, or Thermage
- Avoid exfoliating or scrubbing
- Apply sunscreen regularly and avoid direct sunlight
If you experience abnormal swelling, severe pain, or red rash, contact the clinic for medical evaluation. Results vary depending on individual skin condition.
Collaju vs Filler: What's the Difference?
Many wonder whether to choose Collaju or Filler for younger-looking, plumper skin. While both involve injection under the skin, they serve different purposes:
Filler (HA-type filler)
- Key ingredient: Hyaluronic Acid
- Mechanism: Focuses on "filling" gaps immediately — cheek grooves, chin, or temples
- Results: Visible immediately but may look unnatural if overused
Collaju (Pure Collagen)
- Key ingredient: Atelocollagen (highly pure Type 1 collagen)
- Mechanism: Focuses on "repair and stimulation" (Biostimulator) — acts as a scaffold for skin cells and stimulates natural collagen production
- Results: Skin looks plumper, smoother, and more elastic naturally from within
Summary
Collaju is a Korean skin treatment program using highly pure fresh collagen or "Atelocollagen Type I" injected into the skin to restore deep structure, fill skin for a bouncy look, reduce deep lines, achieve glowing skin, and stimulate long-term collagen production. Ideal for dull, thin skin or those wanting naturally youthful-looking skin.
Orianna Clinic "Beauty in your own"
