Polynucleotides (PN) are biomolecules extracted and purified from salmon DNA, which has a structure similar to human DNA. They support the skin's natural cellular regeneration process (Cellular Regeneration Support).
PN is not a filler, not a botulinum toxin, and not a volumizing agent. Instead, it belongs to the Skin Regenerative Biostimulator group, focused on strengthening skin structure from within.
How Polynucleotides (PN) Work
กลไกการทำงานของ Polynucleotides (PN)
Polynucleotides (PN) are purified DNA fragments processed through biotechnology. They play a role in supporting:
- Fibroblast activity
- Collagen production
- Skin structure regeneration
- Improved skin elasticity
Ideal for those seeking "better skin quality" rather than just temporary volume.
PN works through these main mechanisms:
1. Fibroblast Activation Support
Helps stimulate the cells responsible for producing collagen and elastin.
2. Collagen and Skin Structure Support
Strengthens the dermis layer of the skin.
3. Deep Hydration
PN has water-retaining properties, giving the skin a plump, healthy appearance.
4. Skin Repair Support
Suitable for weakened, thin skin, or skin that has undergone laser treatments.
Who is PN Suitable For?
PN เหมาะกับใคร
PN is ideal for people with:
- Thin, sensitive skin
- Dry skin lacking elasticity
- Fine lines
- Acne scars or uneven skin texture
- Desire for natural skin restoration without volume enhancement
Key Benefits of Polynucleotides
- Focuses on quality skin rejuvenation, not just temporary filling
- Skin appears firmer and smoother gradually
- Delivers natural-looking results
- Can be combined with laser or other procedures
Comparing PN with Other Procedures
เปรียบเทียบ PN กับหัตถการกลุ่มอื่น
1. PN vs Hyaluronic Acid (HA Filler)
| Comparison | PN (Polynucleotides) | HA Filler |
|---|---|---|
| Main Purpose | Skin quality restoration | Filling, adding volume |
| Mechanism | Supports cellular repair | Adds substance to increase volume |
| Result Pattern | Gradual, natural-looking | Fast-visible results |
| Best For | Thin, dull skin | Deep lines, facial structure |
2. PN vs General Skin Boosters
| Comparison | PN | General Skin Booster |
|---|---|---|
| Main Ingredient | DNA Fragment (Polynucleotide) | HA or Vitamins |
| Focus | Skin structure restoration | Adding moisture |
| Result Duration | Continuous | Temporary |
| Best For | Weakened skin needing repair | Dry, dehydrated skin |
3. PN vs Biostimulator (e.g., CaHA / PLLA)
| Comparison | PN | CaHA / PLLA |
|---|---|---|
| Stimulation Intensity | Mild–Moderate | Moderate–High |
| Goal | Fine skin restoration | Enhanced firmness, structure |
| Naturalness | High | Depends on technique |
| Best For | Thin skin, under eyes | Facial contour, hollow cheeks |
Popular Treatment Areas for PN
บริเวณที่นิยมทำ PN
- Under-eye (reduces thinness and fine lines)
- Neck
- Acne scars
- Full-face rejuvenation
Frequently Asked Questions (FAQ)
How is PN different from filler?
PN focuses on restoring skin quality, not on adding volume like fillers do.
When will I see results from PN?
Visible changes in skin quality typically begin within a few weeks and continue to develop with each treatment cycle.
Is PN safe?
It should be performed by a physician at a certified medical facility using products approved by regulatory standards.
Conclusion
PN and PDRN are skin-regenerating substances that help repair skin cells, stimulate collagen, and restore deteriorated tissue to be stronger and smoother.
If you want stronger, smoother, and more youthful-looking skin, PN injections can help rejuvenate your skin at the cellular level, stimulate collagen for firm, tight, and naturally radiant skin. Consult our experienced physicians at Orianna Clinic to choose the skin care approach that best fits your concerns.
Key Takeaway: PN is not just about filling — it's about restoring skin quality from within, for long-term, naturally beautiful, healthy skin.
Orianna Clinic "Beauty in your own"