When skin becomes thinner, elasticity decreases, and fine lines start to show, the problem may not be caused only by a lack of hydration — it can be related to changes in the skin's collagen structure that come with age. The Deusaderm Atelocollagen programme introduces a purified injectable collagen into the skin according to a physician's assessment, with the goal of supporting the skin's structure and helping it look firmer, smoother, and naturally better in quality.
The information in this article is for general education only, not a diagnosis or a guarantee of results. Results, timing, number of sessions, and suitability vary between individuals. Injectable procedures must be performed by a physician at a licensed medical facility.
แพทย์ประเมินผิวก่อนทำโปรแกรม Deusaderm Atelocollagen
What Is Deusaderm Atelocollagen
Deusaderm is an injectable collagen gel manufactured from collagen sourced from Specific Pathogen-Free (SPF) porcine skin, purified by the manufacturer Sunmax Biotech. The term "Atelocollagen" refers to collagen with the telopeptide region — the part associated with triggering an immune response — removed, to reduce the chance of an immune reaction compared with collagen that still contains that region. However, "reduced chance" does not mean there is no risk of allergy or inflammation, so a history must still be taken and an assessment made by a physician every time.
In marketing language, Thai consumers often call this category of product "fresh collagen," but this is not a scientific term indicating the collagen is still alive, and it does not refer to raw animal collagen. A more accurate description is "purified injectable collagen gel" or "purified injectable atelocollagen."
A point that must be communicated transparently is that Deusaderm originates from pigs, not cows. This information is important for those with a history of allergies, and for those with religious, ethical, or personal belief restrictions, and should be part of the informed-decision process.
How Atelocollagen Works with the Skin
โครงสร้างชั้นผิวและเส้นใยคอลลาเจนในชั้นหนังแท้
Collagen is the main structural protein of the extracellular matrix in the dermis, helping support skin strength, elasticity, and smoothness. As we age, and with exposure to sunlight, pollution, smoking, stress, and insufficient rest, the collagen network may decrease or reorganise, making the skin look thinner, drier, and more lax, and more prone to fine lines.
The concept of injectable atelocollagen has two main dimensions:
- Direct structural support — collagen gel is placed in the tissue layer the physician determines, to help support the skin and improve certain types of unevenness.
- Tissue response — the collagen material may act as a temporary scaffold in the extracellular matrix and is associated with the tissue repair process, but the level of new collagen formation and the clinical effect depend on the product formula, technique, position, and individual response.
Deusaderm should therefore not be described as merely a "filling filler," and should not be advertised as being able to create permanent collagen or reverse ageing for certain. The responsible language is "focused on supporting structure and skin quality, with results depending on the physician's assessment and the individual."
What Problems Deusaderm May Help With
A physician may consider the programme depending on the product version, indication, and actual skin condition, such as:
- Skin that is thin or looks tired from a loss of structure
- Fine lines and certain types of uneven texture
- Under-eye skin that looks thin or shows a dark shadow from skin structure — although dark circles from pigment, blood vessels, allergies, or deep-set eye sockets may require a different approach
- Shallow grooves or hollows in certain areas
- Skin quality of the cheeks, around the mouth, neck, or other areas that the product label and physician consider appropriate
- Certain types of acne scars, which may need to be treated together with subcision, laser, radiofrequency, or another method depending on the scar type
Things Deusaderm cannot fix in every case include under-eye bags from loose fat, overactive muscles, significant bone or fat loss, laxity that requires a tightening device or surgery, and abnormal pigmentation that needs specialised treatment. The strength of a good assessment is therefore not choosing the product first, but analysing the "root cause" before designing the programme.
Commonly Assessed Areas
| Area | Key points |
|---|---|
| Under-eye | Suitable for thin skin, fine lines, or uneven skin quality, but this area has blood vessels, delicate anatomy, and swells easily. If the main problem is a deep groove from bone or fat structure, HA filler may also need to be considered. |
| Cheeks and fine lines | May be used to support skin quality and reduce certain kinds of creasing; not the primary choice for building cheekbone volume or reshaping the face where strong support is needed. |
| Nasolabial folds and around the mouth | Must distinguish whether the fold is from bone, fat displacement, skin laxity, or fine lines. Deep structural folds may need HA filler, a tightening device, or a combination plan. |
| Acne scars | Acne scars come in many types, such as rolling, boxcar, and ice-pick. Collagen injection alone is not the answer for every scar; it may need to be planned together with subcision, TCA CROSS, fractional laser, or RF microneedling. |
| Neck | Neck skin is usually thin, moves a lot, and has both horizontal lines and laxity. The problem must be distinguished and the injection level set appropriately; it may be used together with a tightening device or another skin restoration programme. |
Who Is Suitable and Who Should Postpone or Avoid
May be suitable
- Wants to focus on skin quality, firmness, and smoothness rather than a clear change in facial shape
- Has thin skin, fine lines, or certain hollows the physician assesses as suitable
- Accepts a gradual result and individual variation
- Understands that injectable collagen cannot be dissolved with hyaluronidase like HA filler
Must inform the physician in detail or may need to postpone
- Pregnant or breastfeeding
- Infection, inflamed wounds, herpes, or inflamed acne at the treatment site
- History of allergy to porcine collagen, allergy to any component, or a previous severe reaction to an injectable material
- Immune disorders, bleeding disorders, or use of blood-thinning medication
- History of keloids, granulomas, or permanent material at the same site
- Expectations that do not match the limitations of the procedure
- Religious or personal belief restrictions regarding porcine-derived components
Do not stop regular medication, antiplatelet drugs, or blood thinners on your own — always consult the prescribing physician.
Standard Steps to Expect
- Consultation — take a history of drug allergies, underlying conditions, previous procedures, and goals
- Facial & skin analysis — assess skin type, thinness, cause of grooves, and anatomy
- Product verification — check the box, label version, expiry date, distribution source, and relevant registration number
- Treatment planning — determine the position, layer, technique, and volume for the individual
- Aseptic preparation — clean the skin and prepare the area under aseptic technique
- Procedure — the physician performs the procedure according to the plan, using a needle or cannula as appropriate
- Observation & aftercare — assess symptoms immediately, give advice, and schedule follow-up
When Results Begin, How Long They Last, and How Many Sessions Are Needed
ตรวจสอบผลิตภัณฑ์และประเมินประวัติก่อนฉีด Atelocollagen
After the procedure you may see changes from the gel and temporary swelling, so the immediate result should not be taken as the final one. You should wait for the swelling to settle and be assessed at the time the physician schedules. Results in smoothness, firmness, or skin quality may gradually change over several weeks.
There is no single number that applies to everyone for how long results last, because it depends on the product version, volume, position, technique, movement, metabolism, age, behaviour, and other combined plans. The physician will schedule follow-up and design maintenance based on the actual response. The number of sessions is the same — you should not hold to a formula of "everyone needs 3 sessions." Some cases may be satisfied with one session, while others may need a course or another treatment combined.
Does It Hurt, and Is There Downtime
The sensation depends on the position, technique, and individual sensitivity. Local anaesthesia or a product version containing lidocaine may be used as appropriate. Afterward you may notice needle marks, swelling, redness, tightness, tenderness, bruising, or temporary uneven skin, especially under the eyes. Symptoms generally improve gradually, but it should not be guaranteed that everyone will have "no swelling, no bruising, and immediate return to normal activity."
Contact the clinic immediately if: pain worsens abnormally, the skin becomes abnormally pale or purple, there is severe hot swelling and redness, pus, fever, a change in vision, difficulty breathing, or a severe allergic reaction. Eye symptoms or breathing difficulty are medical emergencies and require immediate treatment.
Risks and Limitations You Should Know
Common side effects of injection include pain, swelling, redness, bruising, itching, tenderness, and temporary unevenness. Less common but significant risks include infection, hard nodules, delayed inflammation, granuloma, hypersensitivity reactions, tissue injury, and vascular complications, following the general principles of injectable procedures on the face. Atelocollagen is not an HA filler, so there is no standard dissolving enzyme like hyaluronidase. Choosing a physician who understands anatomy, using a verifiable product, placing the correct layer and volume, and having a system for monitoring complications are therefore all very important.
Care Before and After the Procedure
Before: Disclose all medications, supplements, underlying conditions, allergy history, and previous procedures. Avoid alcohol and activities that increase the chance of bruising. Avoid the procedure on a day with a rash, wound, inflamed acne, or infection. Do not stop physician-prescribed medication on your own, and plan for the possibility of bruising before an important event.
After: Do not press, massage, knead, or apply heat compresses yourself unless instructed by the physician. Keep the area clean and avoid unnecessary contact with the injection site. Avoid strenuous exercise, sauna, intense heat, alcohol, and other procedures for the period the physician specifies. Use only medication the physician recommends, and return for follow-up as scheduled.
Comparing Deusaderm with Other Collagen Injection Brands
All 5 brands should not be called "the same formula," even though they are in a similar collagen injectable category, because they differ in collagen source, protein type, additional components, concentration, cross-linking, indication, and registration status in each country. This must always be confirmed from the IFU or label of the actual version used.
| Brand | Category | Overview | How it differs from Deusaderm |
|---|---|---|---|
| Deusaderm | Purified injectable atelocollagen from SPF porcine skin | Focuses on introducing collagen directly into tissue and supporting skin quality | — |
| Therafill | Porcine atelocollagen filler | Has published research on correcting nasolabial folds with porcine collagen filler | Manufacturer, manufacturing process, formula, concentration, and supporting data differ, even though the main source is also porcine |
| Collaju | Highly purified Type I atelocollagen according to marketing information | Usually positioned for skin quality and thin-skin areas | Formula, manufacturing process, concentration, and brand-specific evidence differ; cc-to-cc comparison is not valid |
| Karisma RH Collagen | Recombinant human collagen with high-molecular-weight HA and CMC | A hybrid bioregenerative formula, not porcine atelocollagen | Collagen source and main components are clearly different, so it is not the same formula |
| Laetigen | Purified Type I collagen injectable from Korea | Usually communicated for firmness, elasticity, pores, and skin quality | Should not be assumed to be the same formula without the IFU, because preparation, concentration, carrier, and indication may differ |
Which brand should you choose? No brand is the best for everyone. The choice should consider 6 factors: the root cause of the problem, the area and skin thickness, the collagen source and allergy history, the formula/concentration/carrier, the evidence and registration of the actual version, and the physician's experience with a system for managing complications.
How Deusaderm Differs from Other Procedure Groups
| Procedure | Difference from Deusaderm |
|---|---|
| HA Filler | Focuses on filling, supporting, and adjusting contour, with a relatively fast visible shape change. Most HA versions can be corrected with hyaluronidase, while Deusaderm focuses on collagen-based tissue support and is not dissolved by that enzyme. |
| PN / PDRN | A polynucleotide-based injectable focused on the skin environment, hydration, and repair, not direct addition of collagen fibres. |
| PLLA | A synthetic collagen biostimulator that stimulates the body's own gradual collagen response, usually used in plans that need wider structural adjustment. |
| CaHA | Provides both scaffold/volume according to the formula and collagen stimulation, popular in areas that need support or skin quality adjustment when used diluted. |
| Profhilo / HA bioremodeling | Uses HA designed to spread and focus on hydration/bioremodeling rather than building shape like a filler; not a direct collagen injection. |
| Energy-based devices | HIFU/MFU, monopolar RF, and other technologies use energy to create a thermal response for tightening or stimulating remodeling, suitable when the main problem is laxity or a certain degree of structural change. |
| Botulinum toxin | Reduces the action of a specific muscle, suitable for wrinkles from facial expression, and does not add collagen or directly correct structural volume loss. |
Frequently Asked Questions About Deusaderm
What is Deusaderm?
It is a purified injectable collagen gel from SPF porcine skin, according to the manufacturer's information, used to support structure and skin quality according to the indication and the physician's judgement.
Is fresh collagen living collagen?
No. It is a marketing term used for injectable collagen. The more accurate term is purified injectable collagen gel.
What is Deusaderm made from?
The manufacturer states it is extracted from SPF porcine skin and purified, so this should be disclosed transparently to the patient before the procedure.
What is Atelocollagen?
It is collagen with the telopeptide region removed to reduce immunogenicity, but this cannot guarantee there is no chance of an allergic reaction.
How is Deusaderm different from HA filler?
HA filler focuses on filling and adjusting shape and can usually be corrected with hyaluronidase, whereas Deusaderm is a collagen-based injectable that is not dissolved by that enzyme.
Can Deusaderm help under the eyes?
It may be suitable for certain types of thin skin, fine lines, or skin quality, but under-eye bags, pigment, blood vessels, or deep grooves have different causes, so a physician must distinguish the problem first.
Does the under-eye area fill in immediately after injection?
You may see an initial change from the gel and swelling, but you must wait for the skin to settle before assessing the actual result.
Does it help all types of under-eye dark circles?
Not all types. Darkness may come from pigment, blood vessels, shadow from the eye socket, allergies, or thin skin — each cause requires different treatment.
Can it help acne scars?
It may be part of a plan for certain types of scars, but each type of acne scar may need to be combined with subcision, TCA CROSS, laser, or RF microneedling.
Does it hurt? How many days of swelling afterward?
The level of sensation differs by area and technique. The physician may use anaesthesia or choose a version with lidocaine. Swelling duration varies, especially under the eyes where it may swell more easily, so allow time before an important event.
When are results seen? How long do they last?
Some changes may be seen quickly, but skin quality should be assessed after swelling subsides and at follow-up over several weeks. How long results last depends on the formula, volume, position, technique, and individual response — do not rely on a single figure from online reviews.
How many sessions are needed? Can you be allergic?
There is no single formula for everyone; the physician will plan based on severity, goal, and response after the first session. Allergy can occur even with purification. Those with a history of allergy or immune disease should inform the physician in detail.
Do I need a skin test before the injection?
This depends on the product label, version, the manufacturer's guidance, and the physician's assessment. The IFU of the actual product used must be checked.
If it forms a lump, can it be dissolved?
Deusaderm is not an HA filler, so hyaluronidase is not used to dissolve it. Management depends on the cause and must be assessed by a physician.
Can it be combined with Botox, filler, or a tightening device?
Some cases can be combined, but the sequence, position, and interval must be set by the physician — do not design the programme yourself.
Can people who avoid porcine products do this?
Deusaderm is sourced from pigs according to the manufacturer's information. Patients should decide based on their own health, religious, ethical, and personal belief considerations.
How do I choose a clinic?
Choose a licensed medical facility, where a physician performs the procedure, uses a verifiable product, explains the risks honestly, and has a system for monitoring complications.
Summary
Deusaderm Atelocollagen is a purified injectable collagen gel from SPF porcine skin, suitable for those who want to gradually support structure and skin quality, but it is not the only answer for every under-eye problem or every area, and it originates from pigs — important information that must be disclosed before deciding. Success in treatment depends on analysing the root cause of the problem before choosing the product.
Consult a physician at Orianna Clinic to assess whether your under-eye concern, thin skin, or fine lines are suitable for Deusaderm or whether another programme should be used, before planning a personalised treatment.
Orianna Clinic "Beauty in your own"