Laetigen is a Type I collagen product for injection into the skin layer. Official information from the Korean brand states a purity of 99.9 percent, while information from the Thai distributor states it is Pure Atelocollagen Type I from porcine skin, at a concentration of 30 mg/mL, packaged as 2 mL per syringe. Actual product information, the Thai-language label, the registration number, and the approved indication in Thailand should be checked from the box the clinic receives for each lot before publishing or advertising.
The term "fresh collagen" is a term the Thai beauty market uses to communicate with consumers; it is not a scientific category name that fully describes the formula. This article therefore uses the term Atelocollagen Type I alongside it for accuracy.
The information in this article is for general education only, not a diagnosis or a guarantee of results. Results, how long they last, volume, and number of sessions vary according to skin condition, position, technique, and the product used, so an individual assessment by a physician is required.
ภาพจำลองชั้นผิวและเส้นใยคอลลาเจนในชั้นหนังแท้
How Atelocollagen Works
Type I collagen is a key structural protein of the skin. Atelocollagen is collagen that has undergone a process to cut off the end section called telopeptide, the region associated with triggering an immune response. This structural adjustment aims to reduce antigenicity, but it does not mean the risk of allergy is zero.
When a physician introduces the product into the appropriate skin layer, the collagen material acts as a temporary component in the extracellular matrix and may help the surface look plumper, firmer, or smoother according to the product's indication. Evidence specific to Laetigen's cosmetic results in humans is still limited, so result figures that are not from the package insert or a verifiable study should be avoided.
Strengths that should be communicated responsibly
- Introduces Type I collagen directly into the skin layer at the position and depth the physician determines
- Focuses on skin quality, elasticity, fine lines, and smoothness rather than a pronounced change in facial shape
- Can be planned for a single spot or multiple areas, depending on the indication, volume, and the physician's assessment
- Suited to communicating results naturally, without guaranteeing a timeframe or using the phrase "definitely see results"
Who May Be Suitable for the Laetigen Programme
บริเวณที่แพทย์อาจประเมินก่อนทำโปรแกรม Laetigen ใบหน้า คอ เนินอก และมือ
- Those who are starting to notice that their skin is thin or elasticity has decreased
- Those with fine lines or uneven skin in an area the physician sees as suitable for the product
- Those who want to look after skin quality and expect a natural change
- Those who understand that results vary and may need to plan for multiple sessions or ongoing care
Who should postpone or avoid: pregnant or breastfeeding; infection or inflammation at the treatment site; a history of allergy to animal-derived collagen or a component of the product; an immune disorder that is not yet controlled; use of medication that affects blood clotting; or having just had another procedure in the same area. These should be disclosed to the physician in detail, and you must never stop medication yourself to receive the treatment.
Areas a Physician May Assess
| Area | Problems commonly brought up | What must be assessed |
|---|---|---|
| Under-eye | Thin skin, fine lines, dryness, or a groove from skin quality | The cause of the groove, skin layer, blood vessels, under-eye bags, and whether another procedure is needed |
| Cheeks and around the mouth | Skin lacking elasticity, fine lines, uneven skin | Muscle movement, lost volume, and tissue laxity |
| Forehead and temples | Thin skin or uneven texture | Depth, position of blood vessels, and whether the goal is skin work or added shape |
| Neck and décolletage | Fine lines and reduced skin quality | Skin thinness, accumulated sun exposure, and any energy-based procedure done together |
| Back of hands | Thin skin and more visible tendons or blood vessels | Level of volume loss and product suitability according to indication |
Laetigen is not the only answer for every area. If the main problem comes from bone, deep fat, muscle, or significant laxity, the physician may consider another method or plan in combination.
Steps to Receive the Service
- The physician takes a history of health, medications, supplements, allergies, and previous procedures
- Assess facial structure, skin quality, the cause of the problem, and expectations
- Verify the product, box, label, registration number, expiry date, and packaging condition in front of the patient
- Clean the skin and prepare for comfort according to the physician's approach
- The physician determines the position, volume, and injection layer suited to each area
- Monitor symptoms afterward and schedule an assessment according to the individual plan
Number of Sessions and Timeframe for Seeing Change
Some Korean clinic sources recommend a course of several sessions about a month apart, but guidance in Thailand must follow the label, indication, skin condition, and the physician's plan; a fixed formula should not be set from an article alone. Early changes may be associated with the added material and mild swelling, while skin quality results must be assessed once post-procedure symptoms have settled. How long results last depends on degradation, volume, position, age, behaviour, and the treatment plan, so it should not be guaranteed as a fixed number of months.
Symptoms After the Procedure and Aftercare
แพทย์ตรวจสอบผลิตภัณฑ์และประวัติก่อนฉีดคอลลาเจน
You may notice needle marks, swelling, redness, pain, soreness, itching, bruising, or temporary bumps.
- Avoid pressing, massaging, scratching, or applying makeup over the openings for the time the clinic recommends
- Avoid intense heat, saunas, alcohol, and strenuous exercise in the early period as the physician advises
- Contact the clinic immediately if pain worsens abnormally, the skin becomes pale or develops dark patches, swelling spreads, there is fever, pus, difficulty breathing, or a severe allergic reaction
Risks to Disclose Before Deciding
Every type of injection carries risk, from temporary symptoms such as swelling, bruising, pain, redness, and itching, to infection, hard nodules, unevenness, allergic reactions, delayed inflammation, or complications from injection into a blood vessel, which are uncommon but can be severe. Risk depends on the product, position, layer, technique, cleanliness, and the patient's health.
Comparing 5 Collagen Brands
This table groups products by their use for skin quality; it does not mean all five brands share the same formula. Information can differ by lot and by country, so labels and package inserts approved in Thailand should be checked before deciding.
| Brand | Country and collagen type | How the formula differs | How to choose |
|---|---|---|---|
| Laetigen | Korea, Pure Atelocollagen Type I from porcine skin | Thai distributor information states 30 mg/mL and 2 mL per syringe | Suited when the physician wants to plan a skin programme directly with Type I atelocollagen |
| TheraFill | Korea, BioCollagen or atelocollagen with telopeptide removed | The manufacturer states it contains lidocaine and is used to adjust wrinkles or folds temporarily | Consider the indication for filling folds and comfort during the procedure according to the label |
| Collaju | Korea, Atelocollagen Type I | The official website states 3 percent collagen | Consider the concentration, product texture, and whether the goal is skin work or support |
| Karisma | Italy, Recombinant Human Collagen alpha 1 chain | Contains high-molecular-weight HA and CMC, so it is not the same formula as Laetigen's porcine atelocollagen | Suited when the physician chooses a bio-restorative formula that emphasises rh collagen working together with HA and CMC |
| Deusaderm | Collagen from SPF porcine skin according to the manufacturer's website | An injectable collagen gel purified through Sunmax's platform | Consider the gel texture, indication, and the physician's experience with the product |
You cannot choose based on brand name alone. Look at whether the main problem is skin work, a shallow groove, volume loss, or laxity from a deep layer. Look at the collagen source and type, additional components, concentration, and volume per syringe. Check the registration status, indication, Thai-language label, and a verifiable import source. Choose a physician who can explain the benefits, limitations, alternatives, and a complication-management plan.
How Laetigen Differs from Other Procedure Groups
| Group | Main mechanism | Suited to goal | Key limitation |
|---|---|---|---|
| Laetigen Atelocollagen | Introduces Type I collagen directly into the skin layer | Skin quality, fine lines, elasticity, and smoothness | Not a deep-layer lift or a substitute for filler in building facial structure in every case |
| HA Skin Booster | Adds hydration and ECM properties according to the formula | Dehydrated skin and skin refinement | Results and timing vary by HA type and formula |
| PN Polynucleotide | Uses polynucleotides to support the skin repair environment | Skin quality and thin-skin areas according to the product | Not direct collagen; evidence and indication vary |
| PLLA / PDLLA / CaHA / PCL | Stimulate the body's own collagen production process | Firmness and structure that need a gradual result | Requires waiting for results; technique and risk are material-specific |
| HA Filler | Adds volume and adjusts shape according to the gel's rheology | Deep grooves, facial structure, and tissue support | Not just a skin quality treatment, and carries vascular risk |
| Energy-based device | Uses energy at the target layer to stimulate contraction or collagen | Laxity, pores, or skin depending on the device type | Does not add material; results depend on the device, energy, layer, and number of shots |
Frequently Asked Questions About Laetigen
What is Laetigen?
It is an injectable Pure Atelocollagen Type I product for use in the skin layer according to the indication and the physician's assessment.
Is Laetigen fresh collagen?
The term fresh collagen is a marketing term used for injectable collagen products; the more accurate term is Type I atelocollagen.
What is Laetigen made from?
Official information in Korea and launch information in Thailand state it is Type I atelocollagen from porcine skin that has undergone a purification process.
How many cc is Laetigen?
The Thai distributor's information states 2 mL per syringe, but the box and actual label should always be checked.
What does Laetigen help with?
It focuses on skin quality, elasticity, smoothness, and fine lines; results depend on the problem and the treatment plan.
Can it be injected under the eyes?
The physician must first distinguish the cause of the under-eye issue, because deep grooves, under-eye bags, blood vessels, thin skin, and pigment each require a different approach.
Where can it be injected?
The position depends on the indication and assessment, such as the face, neck, décolletage, or hands. You should not conclude a position from someone else's review.
Does it hurt? How many days of downtime?
The sensation differs by position, technique, and pain-reduction method used. There are usually needle marks, swelling, redness, or temporary bumps, and recovery time varies, so allow time before an important event.
How many days to see results? How many sessions are needed?
Change may be noticed after swelling subsides, but the result should be assessed at follow-up and the first day's photo should not be taken as the final result. There is no single number of sessions suited to everyone; the physician will consider skin condition, position, response, and the package insert.
How long does it last? Can you be allergic?
How long it lasts depends on degradation, volume, position, age, behaviour, and the treatment plan, so it should not be guaranteed as a fixed number of months. Even though cutting the telopeptide aims to reduce antigenicity, allergy is still possible. Those with a history of allergy to porcine products or severe allergies should inform the physician.
How is it different from filler?
Laetigen focuses on collagen and skin quality, while HA filler focuses on adding volume or adjusting shape according to the gel's properties, though some indications may overlap.
How is it different from Karisma?
Karisma uses recombinant collagen alpha 1 chain together with HA and CMC, so it is a different formula from Laetigen's porcine atelocollagen.
Can it be combined with a tightening device?
It may be planned together, but the sequence and interval must be set by the physician according to the energy type, skin layer, and position.
How do I choose a clinic?
Choose a licensed medical facility, where a physician can verify their own work, the product has a Thai-language label and registration number, and there is a way to follow up on symptoms.
How much does it cost?
Price depends on volume, position, number of sessions, the physician's experience, and follow-up service. Request a quote after assessment and do not decide based on the price per cc alone.
Summary
Laetigen is a purified Type I collagen product for injection into the skin layer, suited to those who want to gradually care for skin quality, elasticity, and fine lines. Choosing to use it requires analysing the root cause of the skin problem and verifying the actual product, rather than choosing based on the brand name alone.
Consult a physician at Orianna Clinic to compare Laetigen with other collagen formulas and choose the plan suited to your problem before deciding.
Orianna Clinic "Beauty in your own"